In addition, the AUCs of the four traditional lung cancer markers were 0.879 for CEA (>3.08 ng/mL), 0.575 for SCC (>1.4 ng/mL), 0.753 for NSE (>15.05 ng/mL), and 0.876 for CYF (>3.16 ng/mL). This evidence concerns the gene ENO2 and lung cancer.