CGN and cyst: It is also important to note that although CGN has also been implicated in organizing the PAN of microtubules in Eph4 cells and regulating cyst morphogenesis (Yano et al., 2013; Mangan et al., 2016), CGN does not interact with CAMSAP3, and CGN-KO mouse tissues do not reveal altered architecture of polarized epithelial cells (Guillemot et al., 2012).