The overall forest plot of the SMD and SROC curves generated through pooling the expression data of CDH11 in the OSCC and non-cancer oral samples from all the included datasets confirmed the significant overexpression of CDH11 in the OSCC tissues and the preferable discriminatory ability of CDH11 expression for OSCC (SMD = 0.88, 95%CI = 0.75–1.01) (AUC = 0.82, 95%CI = 0.78–0.85) (Fig. 6). The gene discussed is CDH11; the disease is cancer.