NFKB1 and laryngotracheoesophageal cleft: In other words, hsa-miR19-3p seems to have lost its function on inhibiting NKRF expression in LC tissues of LC patients without COPD, this is consistent with the detection data of NF-κB p65 phosphorylation in LC tissues of LC patients without COPD is significantly lower than that of LC patients with COPD.