SPTBN1 and adrenal cortex carcinoma: As demonstrated in Table 1, for OS, SPTBN1 had a protective effect on patients with KIRC (HR = 0.53, 95%CI, 0.44–0.64, p = 7.32E-12) and READ (HR = 0.49, 95%CI, 0.28–0.84, p = 0.01), and a detrimental effect on individuals with ACC (HR = 1.77, 95%CI, 1.04–2.99, p = 0.035), BLCA (HR = 1.26, 95%CI, 1.05–1.51, p = 0.014), CESC (HR = 1.67, 95%CI, 1.13–2.47, p = 0.011) and UVM (HR = 1.74, 95%CI, 1.06–2.87, p = 0.029).