In addition, similar studies have shown that Chamomile, with its phytoestrogens and antioxidant properties, reduces FSH levels of testosterone, oxidative stress, estradiol, and LH and improves ovarian histological changes in mice with PCOS by disappearing cysts and increasing the number of follicles [17, 43]. The gene discussed is BRD2; the disease is polycystic ovary syndrome.