Results indicate that ZNF91 (Fig. 11A), and ZNF586 (Fig. 11C) were upregulated in esophageal cancer tissue than adjacent tissue, whereas ZNF502 (Fig. 11B), ZNF865 (Fig. 11D), ZNF106 (Fig. 11E), and ZNF225 (Fig. 11F) was downregulated. The gene discussed is ZNF865; the disease is esophageal cancer.