CD27 and hepatocellular carcinoma: Although there was no significant difference in the number of large cell subset between the 3‐HAA group and HCC group (Figure 2D,E), we found that functional markers CD27 and PD1 were increased in the 3‐HAA group compared to the HCC group, suggesting immune cells were functionally activated after 3‐HAA intervention (Figure 2F,G).