Even with the potential variation with different clones of antibody in mind, literature data and the presented results indicate that SOX10 and TRPS1 are more sensitive breast markers than GATA3, MGB or GCDFP-15 for TNBCs, including their subset expressing CK5 and overlapping in phenotype with squamous carcinomas. The gene discussed is TRPS1; the disease is squamous cell carcinoma.