CD8A and medullary thyroid gland carcinoma: To define the transcriptional profiles of the major subsets of MTC, naïve, TCM, and TEM cells from CD8+ and CD4+ lineages were FACS separated from the blood of four human donors using CCR7 and CD45RA as distinguishing cell surface markers (Fig. 1a, b, and Supplemental Fig. 1a).