Since N-glycans are heterogeneous molecules that are synthesized with different monosaccharides at their termini, and that the process of N-glycan synthesis is cell type- and tissue type-dependent [27–30], we studied the interaction between galectins-1, -3, -7, and -8 and FGFR1 expressed by a panel of human cell lines: human epithelial breast cancer cells (JIMT-1), osteosarcoma cells (G292) and lung small cell carcinoma cells (DMS114). The gene discussed is LGALS1; the disease is breast cancer.