CCND1 and breast cancer: Notably, the EH37E0225350-CCND1 enhancer-gene link scored much lower in other cell lines unrelated to breast cancer, such as HepG2 (Z-score: -0.30), HCT116 (Z-score: 3.07), and K562 (Z-score: −0.20), suggesting that the model has good ability to discriminate between different cellular environments for the same enhancer-gene pair.