Indeed, we observed a significant prolonged survival of Nf1-silenced GBM in qMCP−/−; Cxcl1−/−; Ntv-a mice compared to qMCP−/−;Ntv-a mice, similar what we have shown with Nf1-silenced tumors in Cxcl1−/−; Ntv-a mice (Supplementary Fig. 31). This evidence concerns the gene CXCL1 and glioblastoma.