To extend our discovery to a larger cohort of GBM patients, we culled data from TCGA (cBioportal, Firehose Legacy, 273 GBM patient samples with mutation and copy number alteration (CNA) data) and filtered the samples using criteria so that they only present alterations in one of the following two driver genes— PDGFRA (driver of the PN subtype) or NF1 Del/Mut (MES subtype, Fig. 3D) and lack EGFR alteration. Here, NF1 is linked to glioblastoma.