PDGFB and glioblastoma: We used a previously published method for classifying human GBM cells into distinct and reproducible cellular states (MES-like, AC-like, NPC-like, and OPC-like)13,14, and demonstrate that they are present in our scRNA-seq datasets of PDGFB-driven tumors generated in WT; Ntv-a and qMCP−/−; Ntv-a mice, although with a reduction of OPC- and NPC-like cells and increase in MES-like cells in MCP-deficient tumors compared to WT (Fig. 4A).