MYOM2 and infection: The viral genomes and M protein transcripts were much lower in the lungs than authentic SARS-CoV-2 infection in hamsters, viral reduction during infection showed no signal when evaluated by the viral titration, indicating recombinant SARS-CoV-2 GFP/ΔN virus did not expand and propagate in our Ad5-N–sensitized hamsters but resulted in only a single-cycle infection in hamsters.