In addition, other cancer-related proteins, including SRC-associated protein CUB domain-containing protein 1 (CDCP1/SIMA135/TRASK), platelet-derived growth factor (PDGF)-C and PDGF-D, vascular endothelial growth factor receptor 2 (VEGFR2), and insulin-like growth factor-binding protein-related protein-1 (IGFBP-rP1), are potential substrates of matriptase38. This evidence concerns the gene KDR and cancer.