However, the Oc.N/B.Pm and Oc.S/BS, which were elevated in ALI mice, were decreased significantly in response to Neu Abs against CCL12 compared with IgG (Fig. 2f), suggesting the inhibition of bone resorption in ALI mice in response to the blockade of CCL12 activity. The gene discussed is DDX41; the disease is acute respiratory distress syndrome.