Therefore, we investigated whether the level of SAMHD1 phosphorylated at T592 affected patient prognosis but found no significant difference in the phosphorylation level of SAMHD1 normalized to total SAMHD1 between the normal and tumor tissues of ccRCC patients under various pathological conditions (data not shown). The gene discussed is SAMHD1; the disease is nonpapillary renal cell carcinoma.