P. gingivalis-specific IgG and IgA antibody titres in ESCC patients were significantly higher than those in oesophagitis patients and healthy controls, and the expression levels of the two antibodies were significantly negatively correlated with the survival of oesophageal cancer patients, especially those with stage 0-II or negative lymph node metastasis [43]. This evidence concerns the gene CD79A and esophagitis.