AKT1 and neoplasm: HSPB6 inhibits apoptosis of murine tumor cells and protects against oxidative damage (Ghulmiyyah et al., 2011; Chen et al., 2014), while AKT1 helps mediate cell survival and clonogenic potential (Song et al., 2005; Xu et al., 2012; Gharibi et al., 2014; Liu et al., 2014).