The proportion of CD8 naïve T cells was significantly decreased [percentage: HTN vs. NC, 0.17 vs. 0.30, respectively; p = 0.0015], while the proportion of CD8 TCM cells was comparable between the peripheral blood of normotensive controls and patients with hypertension [percentage: HTN vs. NC, 0.037 vs. 0.034, respectively; p = 0.52] (Supplementary Figure S3). Here, CD8A is linked to hypertensive disorder.