Mental-tranquilization, Invigorating The Brain And Ichihing FruitReduce the levels of inflammatory factors TNF-α, IL-6, IL-1β in serum by inhibiting the activation of astrocytes and microglia, reduce the generation of Aβ and amyloid plaques and increase the Ach content in the cortex, thereby protecting neurons and preventing AD. This evidence concerns the gene TNF and Alzheimer disease.