Sankha Bhattacharya’s study showed that polymeric nanoparticles conjugated with anti-EGFR monoclonal antibody and 5-fluorouracil (5-FU) had higher cellular uptake and higher cytotoxicity, and thereby have a good therapeutic effect on EGFR-positive colorectal cancer (Bhattacharya 2021). The gene discussed is EGFR; the disease is colorectal cancer.