STEAP3 and central nervous system cancer: Multivariate Cox regression analysis indicated that WHO grade (HR = 1.974; 95% CI [1.435–2.716]; P < 0.001), IDH status (HR = 0.290; 95% CI [0.200–0.421]; P < 0.001), and STEAP3 expression level (HR = 1.450; 95% CI [1.045–2.013]; P = 0.026) were independent prognostic factors for glioma patients (Table 3).