STEAP3 and central nervous system cancer: Multivariate Cox regression analysis exhibited that age (HR = 1.496; 95% CI [1.096–2.042]; P = 0.011), WHO grade (HR = 2.622; 95% CI [1.828–3.760]; P < 0.001), IDH status (HR = 0.305; 95% CI [0.198–0.470]; P < 0.001), and STEAP3 expression level (HR = 1.673; 95% CI [1.110–2.522]; P = 0.014) were independent prognostic factors for glioma patients (Table 2).