AGO2 and colorectal carcinoma: Furthermore, RIP assay validated that compared to the control group (anti-IgG), AC125257.1 and miR-133a-3p were noticeably enriched in microribonucleoproteins with Ago2, suggesting that AC125257.1 acted as the ceRNA for miR-133a-3p and formed an RNA-induced silencing complex in CRC cells (Figure 4h).