The most common pathogenic variants in NC-CAH patients were p.Val282Leu (33.33%), CYP21A2 gene deletion/conversion (21.43%), c.293-13A/C>G (14.29%) Pro30Leu (11.90%), which together accounted for more 80% of NC-CAH. This evidence concerns the gene CYP21A2 and congenital adrenal hyperplasia.