The results showed that the expression levels of STAT1, CCR5, NLRP1, IL-15, and CXCL10 were higher in pyroptosis gene cluster B or gene cluster B than in pyroptosis gene cluster A or gene cluster A, which suggested that pyroptosis gene cluster B or gene cluster B is highly linked to RA characterized by the immune response Figure 6C. This evidence concerns the gene STAT1 and rheumatoid arthritis.