Furthermore, we observed significantly increased of hepatic expression of RFX5, ILF3, NFKB1, STAT3, ELF1, SPI1, ETS1 and CEBPA in NAFL and NASH compared to the control group (p < 0.05) (Figure 9B). The gene discussed is STAT3; the disease is metabolic dysfunction-associated steatohepatitis.