HMGCR and metabolic dysfunction-associated steatohepatitis: Grey60 module with hub genes such as FDFT1, NSDHL, IDI1, SQLE, ACSS2, SREBF2, HMGCR, FASN, LSS, ACAT2, FADS1, FADS2 and ELOVL6 was upregulated in NASH (Figure 4C), which were mainly participating in cholesterol and lipid metabolic process (Figure 4C).