Turquoise module was upregulated in NASH patients, contained hub genes related to immune response (CD53, LAPTM5, LCP1, NCKAP1L, C3AR1 and FGL2) (Figure 4B), and enriched for GO categories to cytokine-mediated signaling pathway, neutrophil activation involved in immune response and neutrophil degranulation (Figure 4B). Here, CD53 is linked to metabolic dysfunction-associated steatohepatitis.