PLA2R1 and Hypertension: After adjusting for age, sex, hypertension, proteinuria, albumin, eGFR, PLA2R antibody, and treatment, thyroid dysfunction remained an independent risk factor for IMN relapse (HR = 1.726, P < 0.001) and composite endpoint event (HR = 1.576, P = 0.043), but not for CR (HR = 0.941, P = 0.486) (Table 3).