CHCHD4, CASP3, ACPP, AASDH, CCNH, MAD2L1, and CCNE1 were all significantly upregulated in the ICM-HF group, and TMEM53, P2RY1, and AQP7 were significantly downregulated in the ICM-HF group. This evidence concerns the gene TMEM53 and hydrops fetalis.