The data of NT-proBNP, HA, cTnI, Scr, Tb, AST, ALT, high-sensitivity CRP, fasting glucose, Systolic and male proportion of CHF group were significantly higher than those in healthy group, and LVEF value, Hemoglobin, HDL-C was lower than that in healthy group (P < 0.05). The gene discussed is TNNI3; the disease is congestive heart failure.