To further evaluate the ability of NfL levels within 72 h to predict an mRS ≥ 3 at 6- and 12-months post-stroke, we estimated the area under the ROC curve (AUC) with and without NfL included in the multivariable logistic regression model that included NIHSS and ABC/2 at the time of blood collection. This evidence concerns the gene NEFL and Stroke.