This is further supported by studies who have found higher levels of hs-cTnT to be associated with (sub)clinical brain disease, including white matter hyperintensities and stroke, as well as studies who have found troponin gene expression in the visual cortex, choroid plexus neuroepithelium and hippocampus [8, 9, 33-35]. This evidence concerns the gene TNNT2 and brain disorder.