These same authors employed quantitative real-time PCR and found elevated gluconeogenic enzyme transcript levels (fructose 1,6-bisphosphatase (FBP), glucose-6-phosphatase (G6PC), and phosphor-enolpyruvate carboxykinase (PCK)) in the liver of rodents experiencing cerebrovascular ischemia compared to those undergoing the sham operation. This evidence concerns the gene G6PC1 and brain ischemia.