1. Daple-deficient, Mpdz-deficient, RFX3-deficient, MT1-MMP-deficient, SNX27-deficient [98, 99, 109, 111].2.VPS35 prevents neonatal hydrocephalus [103].3. Inactivation of Cdc42 lead to hydrocephalus [108]. The gene discussed is RFX3; the disease is Hydrocephalus.