PHGDH and hepatocellular carcinoma: The GO/KEGG annotation file downloaded from the GSEA website and the HCC tumor data file were read into R. Analytical operations were performed, and it was found that: the GO of gene PHGDH at HCC was enriched in CHROMATIN REMODELING, DNA PACKAGING, and PROTEIN DNA COMPLEX SUBUNIT ORGANIZATION functions (Figure 12A).