The GO/KEGG annotation file downloaded from the GSEA website and the HCC tumor data file were read into R. Analytical operations were performed, and it was found that: the GO of gene PHGDH at HCC was enriched in CHROMATIN REMODELING, DNA PACKAGING, and PROTEIN DNA COMPLEX SUBUNIT ORGANIZATION functions (Figure 12A). This evidence concerns the gene PHGDH and neoplasm.