Other studies found that LAG3 and HLA-E were associated with immunosuppressive effects and tumor immune evasion in breast cancer, gastric cancer, and ovarian cancer, among others (Woo et al., 2012; Tuncel et al., 2013; Morandi et al., 2014; Zheng et al., 2015; Su et al., 2016; Andrews et al., 2017; Du et al., 2020). The gene discussed is HLA-E; the disease is breast cancer.