Furthermore, heatmap analysis showed that, in the high-risk group, the mRNA expression levels of STX4, UBE2S, EMC6, and EMD were higher, whereas those of NUCB1 and GCAT were lower than those in the low-risk group (Figures 3G, H), suggesting their prognostic-specific roles in PCa patients. Here, STX4 is linked to posterior cortical atrophy.