DYNC2H1 and omphalocele: He et al. find a Chinese fetus carrying compound heterozygous variants of DYNC2H1 gene (c.2225T > G and c.10219C > T) in the fetus with phenotypes including an increased nuchal translucency, a narrow thorax, severely short limbs, postaxial polydactyly of right hand, endocardial cushion defect, megacystis and omphalocele (He et al., 2020).