Moreover, in antibiotic-treated TLR4−/− and MyD88−/− mutant BD mice, UEA1 did not induce colonic fut2 mRNA (Figure 3B, 3rd from right), consistent with the inability of these mutants to express the fuc-TLR4 sentinel receptor, but UEA1 did induce fut2-TLR4 in antibiotic-treated BD TLR2−/− mice (Figure 3B, right), whose TLR4 expression is intact. This evidence concerns the gene TLR2 and Behcet disease.