CRP and rheumatoid arthritis: - Diagnosis of RA according to the ACR/EULAR 2010 criteria within 24 months.- No previous treatment with DMARDs. History of PDN use is allowed but should have been discontinued 2 weeks before baseline measurement.- Active disease with ≥2 painful and ≥ 2 swollen joints in 66/68 joints and CRP ≥2.0 mg/l- Aged 18–80 years