The latest research shows that PRRSV modulates mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) expression to antagonize anti-PRRSV RNases N4BP1 and monocyte chemotactic protein-induced protein (MCPIP1) upon infection, thereby facilitating viral replication (Gu et al., 2022). This evidence concerns the gene MALT1 and infection.