ERBB2 and cancer: Sahlberg KK.et identified a minimal common region of amplication (MCR) including 6 genes covering 78.61 Kb (STARD3, TCAP, PNMT, PERLD1, HER2, and C17orf37) by aCGH analysis, showing that nearly all tumors amplify a considerably larger region, 1.74 Mbp on average, suggesting that many additional genes in the region around HER2 are also amplified and may contribute to the cancer phenotype (4).