They also revealed that STMN1 is a bridge mediating complex crosstalk between HCC cells and HSCs by enhancing hepatocyte growth factor (HGF)/MET signal pathway and that STMN1‐induced PDGF secreted by HCC cells may be responsible for activating HSC to acquire CAF features and secrete more HGF (88). This evidence concerns the gene HGF and hepatocellular carcinoma.