HRD has been linked with genetic or epigenetic impairment of genes belonging to the BRCA-pathway such as BRCA1, BRCA2, PALB2 and RAD51B, RAD51C and RAD51D, but BRCA1 is the most frequently affected gene in TNBC (5, 6). This evidence concerns the gene RAD51C and hypoparathyroidism-retardation-dysmorphism syndrome.