TLR4 and neoplasm: Furthermore, a significant reduction was observed in the transcripts of the microbial sensors, Toll-like receptors (TLR)–2, TLR-5, and TLR-9 (p = 0.0298, p = 0.0201, and p = 0.0021, respectively) was observed in tumour tissue while there was a similar expression level of TLR1, TLR4, and TLR6 in healthy and tumour tissue.