When the eight characteristic genes (ENTPD3, PDZD4, CNN1, GTPBP4, FPGS, UTP25, CENPW, and FAM111A) are all fitted into one variable, the AUC of the ROC curve is 0.996, indicating a good diagnostic efficiency for gastric cancer (Figures 5B, C). This evidence concerns the gene PDZD4 and gastric cancer.