CD4 and cancer: Compared with adjacent tissues, the proportion of B cell plasma, T cell CD4+memory resetting, Monocyte, and mast cell activated in the cancer group is relatively high, while the proportion of T cell CD4+memory activated, T cell follicular helper, T cell regulatory (Tregs), Macrophage M0, Macrophage M1, and mast cell resetting is relatively low (Figures 7A, B).