CD274 and small cell lung carcinoma: Moreover, the results of Point biserial correlation analysis between PNI and DCR showed that patients who had a higher increase in PNI trend had better DCR compared with those with a higher decrease in SCLC patients treated with PD-L1/PD-1 inhibitors monotherapy or combined with chemotherapy (r = 0.351, p < 0.001; r = 0.285, p < 0.001, respectively) (Tables 2, 3).