In a previous study, among the murine experimental autoimmune encephalomyelitis (EAE) model once the mice were immunized with the myelin oligodendrocyte glycoprotein (MOG) peptide, the proportion of Tfh cells on the 7th day post-immunization was far lower than on the 14th day, and it decreased again on the 21st day (Zotos et al., 2010), which was in line with our findings. Here, MOG is linked to experimental autoimmune encephalomyelitis.