The most promising pathways for LMQXM treatment of ADHD, according to GO and KEGG pathway enrichment analysis, are serotonergic synapse, neuroactive ligand-receptor interaction, the PI3K-Akt signaling pathway, the calcium signaling pathway, dopaminergic synapse, the cAMP signaling pathway, Alzheimer disease, the MAPK signaling pathway, and so on. This evidence concerns the gene AKT1 and attention deficit-hyperactivity disorder.