In experimental elastase-induced emphysema, BM-MSCs with cis-resveratrol-induced Hsp70 promoter-regulated VEGFA expression were infused and demonstrated to enhance lung function and levels of VEGF and anti-oxidant mediators (HO-1, Nrf2 and SOD), and reduced lung structural abnormalities (Chen et al., 2015b). This evidence concerns the gene VEGFA and pulmonary emphysema.