IL4 and allergic asthma: In experimental ovalbumin-induced allergic asthma, activation of BM-MSC TLR2 by the agonist Pam3CSK4 led to a reduction in levels of BALF TH2 cytokines (IL-4 and IL-5) and eosinophil counts in lungs, resulting in attenuation of airway resistance in response to incremental doses of methacholine (Yu and Chiang, 2018).